Growth curve analysis of Effect of Maternal Cocaine Use on Child Growth

Recently a lot of attention has been given to the analysis of longitudinal data and repeated measures. Several issues dealing with il-conditioned observations, ie, missing observations, censored observations and irregular sampling have been addressed in the recent literature. We revisit the condition where observations are made at irregular sampling time and offer a comparable and intrinsic solution to this problem. To show this procedure we will describe the analysis of growth curves generated from a cohort of children measured from birth using three characteristics: height (centimeters), weight (in kilograms), and head circumference (centimeters). The significant chracteristic being that of an irregular sampling rate. We address these issues in assessing the association of maternal cocaine abuse on the observations. ===========================================================